General Information
|
|
Product
|
ETS1 associated protein II Peptide
|
Description
|
Antigenic Blocking Peptide tyrosyl-DNA phosphodiesterase 2 Antibody
|
Verified Applications
|
Immunocompetition, Immunodepletion
|
Peptide Description
|
Synthetic peptide taken within amino acid region 330-360 on human Tyrosyl-DNA phosphodiesterase protein.
|
Accession #
|
NCBI: NP_057698.2
|
Physical Properties
|
|
Quantity
|
250 µg
|
Volume
|
100 µl
|
Form
|
Antigenic Blocking Peptide
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
Competition/Depletion assay
|
Refer to competition assay protocol
|
Protein
|
Uniprot #
|
O95551
|
Overview
|
DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue.
|
Molecular Function
|
5'-tyrosyl-DNA phosphodieseterase activity, magnesium ion binding, manganese ion binding, nuclease activity, transcription corepressor activity, single-stranded DNA binding
|
Subcellular Location
|
nucleus, PML body, cytoplasm
|
Expression
|
Widely expressed
|
Alternative Nomenclature
|
5'-tyrosyl-DNA phosphodiesterase antibody
AD 022 antibody
dJ30M3.3 antibody
EAP 2 antibody
ETS 1 associated protein 2 antibody
RP1-30M3.3 antibody
TRAF and TNF receptor associated protein antibody
TTRAP antibody
Tyr DNA phosphodiesterase 2 antibody
|
|
|