General Information
|
|
Product
|
Myosin 1C Antibody
|
Description
|
Affinity Purified Unconventional Myosin-Ic / Myo 1C Antibody
|
Verified Applications
|
ELISA, IHC, IP, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Mouse
|
Immunogen
|
Synthetic peptide taken within amino acid region 1-50 on mouse Unconventional Myosin-Ic / Myo 1C.
|
Accession #
|
NCBI: NM_001080775
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
0.5-1.5 µg/µl in antibody stabilization buffer
|
Immunoglobulin
|
IgG
|
Form
|
Affinity Purified
|
Purification Method
|
Immobilized antigen affinity chromatography
|
Clonality
|
Polyclonal
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
ELISA
|
1:50,000
|
Immunohistochemistry |
1:50-1:150 |
Immunoprecipitation
|
1:200
|
Western Blot
|
1:2,500-1:5,000
|
Protein
|
Uniprot #
|
Q9WTI7
|
Overview
|
actin binding
actin-dependent ATPase activity
actin filament binding
ATP binding
calmodulin binding
microfilament motor activity
phospholipid binding
protein C-terminus binding
Ral GTPase binding
signaling receptor binding
|
Molecular Function
|
Cell membrane, Cytoplasm
|
Expression
|
Binds directly to large unilamellar vesicles (LUVs) containing phosphatidylinositol 4,5-bisphosphate (PIP2) or inositol 1,4,5-trisphosphate (InsP3). The PIP2-binding site corresponds to the myosin tail domain (PH-like) present in its tail domain.
|
Structure
|
Unconventional Myosin-Ic / Myo 1C
|
Alternative Nomenclature
|
MMI beta antibody
MMIb antibody
MYO1C antibody
Myosin I beta antibody
Myosin-Ic antibody
MYR2 antibody
NMI antibody
Nuclear myosin I antibody
|
|
|