General Information

Product

P2Y2 Antibody

Description

Affinity Purified P2Y purinoceptor 2 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Cat, Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 360-410 on rat P2Y2 protein.

Accession #

GenBank: EAW74883.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.52-0.68 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

A0A024R5N1

Overview

Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP.

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Membrane

Expression

Spleen, testis, kidney, liver, lung, heart and brain.

Structure

Belongs to the G-protein coupled receptor 1 family.

Alternative Nomenclature

ATP receptor antibody

HP2U antibody

Human P2U nucleotide receptor mRNA complete cds antibody

MGC20088 antibody

MGC40010 antibody

P2RU1 antibody

P2RY2 antibody

P2U antibody

P2U nucleotide receptor antibody

P2U purinoceptor 1 antibody

P2U receptor 1 antibody

P2U1 antibody

P2UR antibody

P2Y purinoceptor 2 antibody

P2Y2 antibody

P2Y2R antibody

Purinergic receptor antibody

Purinergic receptor P2Y G protein coupled 2 antibody

Purinergic receptor P2Y2 antibody

Purinoceptor P2Y2 antibody

General Information

Product

Phospho-ACK1 Antibody Antibodyd

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-300 on ACK1 protein. 

Accession #

GenBank: AAL55732.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-1.25 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

Dot Blot

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P13749

Overview

Plays a role in presenting foreign antigens to the immune system.

Molecular Function

peptide antigen bonding

Subcellular Location

Membrane; Single-pass type I membrane protein

Structure

Heterodimer of an alpha chain and a beta chain

Alternative Nomenclature

Acetate kinase 1 antibody

ACK 1 antibody

ACK antibody

Activated Cdc42 associated kinase 1 antibody

Activated p21cdc42Hs kinase antibody

FLJ44758 antibody

FLJ45547 antibody

p21cdc42Hs antibody

TNK 2 antibody

Tyrosine kinase non receptor 2 antibody

General Information

Product

PAR2 Antibody

Description

Affinity Purified Proteinase-activated receptor 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Chimpanzee, Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 300-370 of mouse PAR2.

Accession #

NCBI:  NP_032000.3

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.62 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:15,00-1:20,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:250

Protein

Uniprot #

P55086

Overview

Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.

Structure

Interacts with TLR4, COPS5 and TMED2.  Also interacts with GNAQ, GNA11, GNA12, GNA13, and GNA14.

Alternative Nomenclature

Coagulation factor II receptor like 1 

Coagulation factor II thrombin receptor like 1

F2RL1 

G protein coupled receptor 11 

GPR11 

PAR 2 

Proteinase activated receptor 2

Thrombin receptor like 1 

General Information

Product

PDE4B3 Antibody

Description

Affinity Purified cAMP-specific phosphodiesterase PDE4B Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide selective only for PDE4B3 subtype.

Accession #

GenBank: AAB96560.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P14646

Overview

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Molecular Function

Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding

Expression

Widely expressed. Isoform 3 expressed in brain, heart, lung and liver. Isoform 4 expressed in liver and brain.

Alternative Nomenclature

DPDE4 antibody

PDE IVB antibody

Phosphodiesterase 4B antibody

Phosphodiesterase Type 4B3 antibody

General Information

Product

PDE4B4 Antibody

Description

Affinity Purified cAMP-specific phosphodiesterase isoform PDE4B4 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide selective only for PDE4B4 protein.

Accession #

GenBank: AAL31764.1 

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:250-1:500

Protein

Uniprot #

P14646

Overview

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Molecular Function

Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding

Expression

Widely expressed. Isoform 3 expressed in brain, heart, lung and liver. Isoform 4 expressed in liver and brain.

Alternative Nomenclature

cAMP dependent phosphodiesterase type B antibody

cAMP specific 3 5 cyclic phosphodiesterase 4B antibody

CAMP specific phosphodiesterase isoform PDE4B4 antibody

DPDE4 antibody

Dunce like phosphodiesterase E4 antibody

MGC126529 antibody

PDE4B 4 antibody

PDEIVB antibody

Phosphodiesterase 4B cAMP specific antibody

Phosphodiesterase E4 dunce homolog antibody

Phosphodiesterase E4 dunce homolog Drosophila antibody

General Information

Product

PDE4D Antibody

Description

Affinity Purified Phosphodiesterase 4D Antibody

Verified Applications

ELISA, IP, ICC/IF, IHC-P, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

C-terminal cyclic peptide unique to all PDED subtypes variants.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.57 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Overview

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Molecular Function

Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding

Subcellular Location

Apical cell membrane, Cytoplasm, Membrane

Expression

Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.

Structure

Homodimer for the long isoforms. Isoforms with truncated N-termini are monomeric. Isoform 3 is part of a ternary complex containing PRKAR2A, PRKAR2B and AKAP9. Interacts with PDE4DIP. Identified in a complex composed of RYR1, PDE4D, PKA, FKBP1A and protein phosphatase 1 (PP1).

Alternative Nomenclature

cAMP specific 3',5' cyclic phosphodiesterase 4D antibody

DKFZp686M11213 antibody

5''-cyclic phosphodiesterase 4D antibody

cAMP specific phosphodiesterase PDE4D antibody

cAMP specific phosphodiesterase PDE4D6 antibody

DPDE 3 antibody

Dunce like phosphodiesterase E3 antibody

FLJ97311 antibody

HSPDE4D antibody

PDE 43 antibody

PDE4DN2 antibody

Phosphodiesterase 4D cAMP specific (dunce (Drosophila) homolog phosphodiesterase E3) antibody

Drosophila antibody

STRK1 antibody

General Information

Product

PDE4D1 Antibody

Description

Affinity Purified Phosphodiesterase 4D1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Chicken, Mouse, Rat

Immunogen

Synthetic peptide from unique region near N-terminus of PDE4D1 variant.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.73 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Overview

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Molecular Function

Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding

Subcellular Location

Apical cell membrane, Cytoplasm, Membrane

Expression

Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.

Structure

Homodimer for the long isoforms. Isoforms with truncated N-termini are monomeric. Isoform 3 is part of a ternary complex containing PRKAR2A, PRKAR2B and AKAP9. Interacts with PDE4DIP. Identified in a complex composed of RYR1, PDE4D, PKA, FKBP1A and protei

Alternative Nomenclature

cAMP specific 3',5' cyclic phosphodiesterase 4D antibody

DKFZp686M11213 antibody

5''-cyclic phosphodiesterase 4D antibody

cAMP specific phosphodiesterase 4D antibody

cAMP specific phosphodiesterase PDE4D antibody

DPDE 3 antibody

Dunce like phosphodiesterase E3 antibody

FLJ97311 antibody

HSPDE4D antibody

PDE 43 antibody

PDE4DN2 antibody

Phosphodiesterase E3 dunce homolog Drosophila antibody

STRK1 antibody

General Information

Product

PDE4D2 Antibody Affinity Purified

Description

Affinity Purified Phosphodiesterase 4D2 Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Chicken, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on PDE4D2 variant gene.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.76 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Overview

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Molecular Function

Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding

Subcellular Location

Apical cell membrane, Cytoplasm, Membrane

Expression

Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.

Structure

Homodimer for the long isoforms. Isoforms with truncated N-termini are monomeric. Isoform 3 is part of a ternary complex containing PRKAR2A, PRKAR2B and AKAP9. Interacts with PDE4DIP. Identified in a complex composed of RYR1, PDE4D, PKA, FKBP1A and protein phosphatase 1.

Alternative Nomenclature

cAMP specific 3',5' cyclic phosphodiesterase 4D antibody

DKFZp686M11213 antibody

cAMP-specific 3'' antibody

cyclic AMP phosphodiesterase antibody

DPDE 3 antibody

FLJ97311 antibody

HSPDE4D antibody

PDE43 antibody

PDE4DN2 antibody

Phosphodiesterase 4D, cAMP specific (dunce) antibody

Phosphodiesterase E3 dunce homolog Drosophila antibody

STRK 1 antibody

General Information

Product

PDE4D3 Antibody

Description

Affinity Purified cAMP-specific phoshodiesterase HPDE4D3 variant Antibody

Verified Applications

CM, ELISA, ICC/IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Chicken, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on PDE4D3 variant.

Accession #

GenBank: EAW74861.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q08499

Overview

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Molecular Function

Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding

Subcellular Location

Apical cell membrane, Cytoplasm, Membrane

Expression

Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.

Structure

Homodimer for the long isoforms. Isoforms with truncated N-termini are monomeric. Isoform 3 is part of a ternary complex containing PRKAR2A, PRKAR2B and AKAP9. Interacts with PDE4DIP. Identified in a complex composed of RYR1, PDE4D, PKA, FKBP1A and protein phosphatase 1 (PP1).

Alternative Nomenclature

DPDE3 antibody

hPDE4D3 antibody

HSPDE4D antibody

PDE43 antibody

PDE4D antibody

PDE4DN2 antibody

Phosphodiesterase 4D antibody

Phosphodiesterase 4D cAMP-specific antibody

Phosphodiesterase Type 4D3 antibody

STRK1 antibody

General Information

Product

PDE4D9 Antibody

Description

Affinity Purified Phosphodiesterase 4D9 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Chicken, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on PDE4D9 variant gene.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.2 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500-1:1,000

Protein

Overview

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Molecular Function

Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding

Subcellular Location

Apical cell membrane, Cytoplasm, Membrane

Expression

Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.

Structure

Homodimer for the long isoforms. Isoforms with truncated N-termini are monomeric. Isoform 3 is part of a ternary complex containing PRKAR2A, PRKAR2B and AKAP9. Interacts with PDE4DIP. Identified in a complex composed of RYR1, PDE4D, PKA, FKBP1A and protei

Alternative Nomenclature

cAMP specific 3',5' cyclic phosphodiesterase 4D antibody

DKFZp686M11213 antibody

5''-cyclic phosphodiesterase 4D antibody

cAMP specific phosphodiesterase 4D antibody

cAMP specific phosphodiesterase PDE4D antibody

DPDE 3 antibody

Dunce like phosphodiesterase E3 antibody

FLJ97311 antibody

HSPDE4D antibody

PDE 43 antibody

PDE4DN2 antibody

Phosphodiesterase E3 dunce homolog Drosophila antibody

STRK1 antibody