General Information
|
|
Product
|
FPR1 Peptide
|
Description
|
Antigenic Blocking Peptide N-formyl peptide receptor
|
Verified Applications
|
Immunodepletion, Immunocompetition
|
Peptide Description
|
Synthetic peptide taken within amino acid region 150-200 on N-formyl peptide receptor.
|
Accession #
|
GenBank: AAA16863.1
|
Physical Properties
|
|
Quantity
|
250 µg
|
Volume
|
100 µl
|
Form
|
Antigenic Blocking Peptide
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
Competition/Depletion assay
|
Refer to competition assay protocol
|
Protein
|
Uniprot #
|
P21462
|
Overview
|
High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors (PubMed:2161213, PubMed:2176894, PubMed:10514456, PubMed:15153520). Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release (PubMed:2161213, PubMed:1712023, PubMed:15153520). This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:1712023, PubMed:10514456).
|
Molecular Function
|
N-formyl peptide receptor activity; Receptor activity
|
Subcellular Location
|
Cell membrane; Multi-pass membrane
|
Structure
|
Belongs to the G-protein coupled receptor 1 family.
|
Alternative Nomenclature
|
fMet Leu Phe receptor antibody
FMLP antibody
FMLPR antibody
Formyl peptide receptor 1 antibody
FPR 1 antibody
FPR receptor antibody
N formyl peptide chemoattractant receptor antibody
N formyl peptide receptor antibody
|
|
|