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General Information
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Product
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Eprhin Receptor A6 Antibody Affinity Purified
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Description
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Affinity Purified Ephrin type-A receptor 6 isoform A Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 800-900 on human EphA R6 protein.
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Accession #
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NCBI: NP_001073917
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Western Blot
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1:500
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Protein
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Uniprot #
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B3KS12
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Overview
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Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).
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Molecular Function
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ATP-binding, Nucleotide-binding
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Subcellular Location
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Membrane; Single-pass type I membrane protein
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Expression
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Expressed in brain and testis.
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Structure
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Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses (By similarity).
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Alternative Nomenclature
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Ehk 2 antibody
EPH homology kinase 2 antibody
Eph Receptor A6 antibody
ephrin receptor EphA6 antibody
Hek12 antibody
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Ephrin Receptor A6 Antibody FITC
Ephrin Receptor A6 Antibody BIOTIN
Ephrin Receptor A6 Blocking Peptide
Ephrin Receptor A6 Positive Control
