General Information |
|
Product |
ADCY7 Antibody FITC-Conjugated |
Description |
FITC-Conjugated Adenylate cyclase type 7 Antibody |
Verified Applications |
CM, ELISA, ICC/IF, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Bovine, Human, Mouse, Rat |
Immunogen |
Synthetic peptide corresponding to unique amino acid sequence on mouse Particulate Adenylyl Cyclase 7 protein. |
Specificity | This antibody does not cross react with other Adenylate cyclases. |
Accession # |
NCBI: NP_031432.2 |
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|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.75 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
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|
Confocal Microscopy |
1:100-1:200 |
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunocytochemistry |
1:100-1:200 |
Immunofluorescence |
1:100-1:200 |
Immunohistochemistry |
1:100-1:200 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
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Uniprot # |
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Overview |
Membrane bound calcium-inhibitable adenylyl cyclase. |
Molecular Function |
Adenylate cyclase activity; cAMP biosynthesis; ATP-binding; Magnesium; Metal binding; Nucleotide-binding |
Subcellular Location |
Membrane; Multi-pass membrane |
Expression |
Heart, spleen and lung |
Structure |
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Contains 2 guanylate cyclase domains. |
Alternative Nomenclature |
adenylate cyclase 7 antibody adenylyl cyclase antibody ATP pyrophosphate-lyase antibody KIAA0037 antibody |
Protein information supplied by UniProt
Fabgennix ADCY7 Antibody has been used in 4 Publications |
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Kwon, Ronald Y. et al. “Primary Cilium-Dependent Mechanosensing Is Mediated by Adenylyl Cyclase 6 and Cyclic AMP in Bone Cells.” The FASEB Journal 24.8 (2010): 2859–2868. PMC2909282
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Confocal Microscopy, Immunofluorescence; Human |
Masyuk, Anatoliy I. et al. “Cholangiocyte Primary Cilia Are Chemosensory Organelles That Detect Biliary Nucleotides via P2Y12 Purinergic Receptors.”American Journal of Physiology - Gastrointestinal and Liver Physiology295.4 (2008): G725–G734. PMC2575915
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Confocal Microscopy, Immunofluorescence; Rat |
Stout, Sarah L., et al. "Nitric oxide-dependent cilia regulatory enzyme localization in bovine bronchial epithelial cells." Journal of Histochemistry & Cytochemistry 55.5 (2007): 433-442. PMID17242464
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Immunohistochemistry, Western Blot; Bovine |
Kolachala, Vasantha, et al. "Interferon-γ down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase." Journal of Biological Chemistry 280.6 (2005): 4048-4057. PMID15550390
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Western Blot; Human |
Publishing research using PAC-701AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
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PAC-701AP | |||
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P-PAC7 | |||
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PAC7-BIOTIN | |||
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PC-PAC7 | |||
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