General Information |
|
Product |
SERINC5 Antibody FITC |
Description |
FITC-Conjugated Serine incorporator 5 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Monkey |
Immunogen |
Synthetic peptide taken within amino acid region 270-320 on human Serine incorporator 5 protein. |
Accession # |
NCBI: XP_011541606 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:10,000 |
Immunohistochemistry | 1:50-1:150 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Restriction factor required to restrict infectivity of gammaretroviruses, such as HIV-1: acts by inhibiting early step of viral infection and impairing the ability of the viral particle to translocate its content to the cytoplasm (PubMed:26416733, PubMed:26416734). Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes. |
Molecular Function |
L-serine transmembrane transporter activity |
Subcellular Location |
Cell membrane; Multi-pass membrane |
Expression |
Highly expressed in placenta, skeletal muscle, spleen, thymus, testis and peripheral leukocyte and is expressed weakly in the heart, liver and fetal brain. |
Structure |
Belongs to the TDE1 family |
Alternative Nomenclature |
C5orf12 antibody SERC5_HUMAN antibody SERINC5 antibody Serine incorporator 5 antibody TPO1 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-SERC5 | |||
|
PC-SERC5 | |||
|
SERC5-501AP | |||
|
SERC5-BIOTIN | |||
Display accessory details |
Select your currency:
(c) FabGennix International Inc.