General Information

Product

TM6SF2 Antibody

Description

Affinity Purified Transmembrane 6 superfamily member 2 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 325-375 on human TM6SF2 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68-0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:150

Western Blot

1:250

Protein

Uniprot #

Q8R1J1

Molecular Function

Integral component of membrane

Structure

Transmembrane helix; Belongs to TM6SF family

Alternative Nomenclature

TM6S2_HUMAN antibody

tm6sf2 antibody

Transmembrane 6 superfamily member 2 antibody

General Information

Product

TM6SF2 Antibody

Description

Affinity Purified Transmembrane 6 superfamily member 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 220-270 on mouse TM6SF2 protein.

Accession #

NCBI:  NP_001001524

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68-0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:150

Western Blot

1:250

Protein

Uniprot #

Q9BZW4

Molecular Function

Integral component of membrane

Structure

Transmembrane helix; Belongs to TM6SF family

Alternative Nomenclature

TM6S2_HUMAN antibody

tm6sf2 antibody

Transmembrane 6 superfamily member 2 antibody

General Information

Product

DRP1 Antibody

Description

Dynamin-related Protein 1 Antibody

Verified Applications

ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

D. Melanogaster, Human, Mouse, Rat

Immunogen

Synthetic peptide within 450-490 on human DRP1 protein.

Accession #

GenBank: BAC06576.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.68 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Clonality

Polyclonal

Storage

-20°C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:450

Protein

Uniprot #

Q8K1M6

Overview

Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism.

Molecular Function

GTP-binding, Lipid-binding, Nucleotide-binding

Subcellular Location

Golgi apparatus; Peripheral membrane protein; peroxisome; Mitochondrion outer membrane; Clathrin-coated pit; synaptic vesicle membrane

Expression

Expressed in the cerebellum and in several regions of the cerebrum and diencephalon

Structure

Homotetramer; dimerizes through the N-terminal GTP-middle region of one molecule binding to the GED domain of another DNM1L molecule. Oligomerizes in a GTP-dependent manner to form membrane-associated tubules with a spiral pattern. Can also oligomerize to form multimeric ring-like structures.

Alternative Nomenclature

DLP1 antibody

dnm1l antibody

Dnm1p/Vps1p-like protein antibody

dnml1 antibody

DRP1 antibody

DVLP antibody

Dymple antibody

Dynamin 1 like antibody

Dynamin family member proline-rich carboxyl-terminal domain less antibody

Dynamin like protein antibody

Dynamin-like protein 4 antibody

Dynamin-related protein 1 antibody

DYNIV 11 antibody

EMPF antibody

FLJ41912 antibody

HdynIV antibody

VPS1 antibody

General Information

Product

SLC29A3 Antibody Affinity Purified

Description

Affinity Purified Equilibrative Nucleoside Transporter 3 isoform A Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-60 on ENT3 protein.

Accession #

NCBI: NP_060814.4

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9BZD2

Overview

Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter)

Molecular Function

nucleoside transmembrane transporter activity

Subcellular Location

Endosome, Lysosome, Membrane

Expression

Widely expressed in both adult and fetal tissues. Highest levels in placenta, uterus, ovary, spleen, lymph node and bone marrow. Lowest levels in brain and heart

Structure

Belongs to the SLC29A/ENT transporter (TC 2.A.57) family

Alternative Nomenclature

ENT3 antibody

Equilibrative nucleoside transporter 3 antibody

HCLAP antibody

hENT3 antibody

HJCD antibody

PHID antibody

SLC29A3 antibody

solute carrier family 29 (equilibrative nucleoside transporter), member 3 antibody

General Information

Product

CRMP3 Antibody

Description

Affinity Purified Dihydropyrimidinase related protein 4 Antibody

Verified Applications

ELISA, WB

Species Cross Reactivity

Cat, Human, Monkey, Mouse, Pig, Rat

Immunogen

Synthetic peptide corresponding to amino acids 509-527 of Mouse CRMP3. The peptide was covalently modified to achieve the desired antigenicity before coupling to carrier protein.

Sequence:

PAKPGSGTQARASCSGKIS

Accession #

NCBI: NP_006417.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20°C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:450

Protein

Uniprot #

O14531

Overview

Necessary for signaling by class 3 semaphorins and subsequent remodeling of cytoskeleton.  Plays a role in axon guidance, neuronal growth cone collapse and cell migration.

Molecular Function

Axon guidance; pyrimidine nucelobase catabolic process; Nervous system development

Subcellular Location

Cytoplasm

Structure

Homotetramer.

Alternative Nomenclature

Collapsin response mediator protein 3 antibody

DPYSL4 antibody

DRP4 antibody

ULIP 4 antibody

UNC33 like phosphoprotein 4 antibody

General Information

Product

ASNA1 Antibody

Description

Affinity Purified Arsenate activated ATPase Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 300-348 on human ATPase ASNA1 protein.

Accession #

NCBI:  NP_004308

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.52-.53 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

O43681

Overview

ATPase required for post-translational delivery of tail-anchored proteins to the ER

Molecular Function

ATP binding; Metal-binding; Nucleotide binding; Zinc

Subcellular Location

Cytoplasm; Endoplasmic Reticulum; Nucleus

Expression

Epithelial cells of liver, kidney, stomach wall, islet cells of pancreas, red pulp of spleen and cardiac and skeletal muscle.

Structure

Homodimer. Component of transmembrane domain recognition complex.

Alternative Nomenclature

ARSA 1 antibody

ArsA arsenite transporter ATP binding homolog 1 antibody

GET3 antibody

Golgi to ER traffic 3 homolog antibody

Transmembrane domain recognition complex, 40kDa antibody

TRC40 antibody

General Information

Product

BTBD3 Antibody

Description

Affinity Purified BTBD/ POZ domain containing protein 3 isoform A Antibody

Verified Applications

ELISA, IHC, IPP, WB

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 410-460 on human BTBD3 protein.

Accession #

NCBI: NP_055777

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9Y2F9

Overview

Acts as a key regulator of dendritic field orientation during development of sensory cortex. Directs dendrites toward active axon terminals.

Molecular Function

Neurogenesis

Subcellular Location

Cytoplasm; Nucleus

Structure

Contains BACK domain and BTB domain

Alternative Nomenclature

BTB/POZ domain-containing protein 3 antibody

dJ742J24.1 antibody

General Information

Product

BTBD7 Antibody

Description

Affinity Purified BTB/POZ domain containing protein 7 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Species Cross Reactivity

Human, Mouse

Immunogen

Synthetic peptide taken within amino acid region 1050-1150 on human BTBD7 protein.

Accession #

NCBI: NP_001002860

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61-0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9P203

Overview

Mediator of epithelial dynamics and organ branching by promoting cleft progression.

Molecular Function

Developmental proteins

Subcellular Location

Nucleus

Expression

Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppresion of E-cadherin levels.

Alternative Nomenclature

5730507E09Rik antibody

8030448M07 antibody

BTBD7 antibody

E130118E17Rik antibody

FUP1 antibody

General Information

Product

Glucose-6-Phosphate, catalytic subunit Antibody Affinity Purified

Description

Affinity Purified Glucose-6-phosphoate catalytic 2 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 80-130 on G6PC2 protein, and common in larger variant of glucose 6 phosphatase.

Accession #

GenBank: CAM24718

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9Z186

Overview

May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis.

Molecular Function

Gluconeogenesis

Subcellular Location

Endoplasmic Reticulum Membrane; Multi-pass membrane protein

Expression

Specifically expressed in pancreatic islet cells, in particular those of beta-cell origin. Not detected in testis, kidney, muscle, liver, lung, spleen, brain, pituitary, gastric fundus or heart.

Structure

Belongs to the glucose-6-phosphatase family.

Alternative Nomenclature

AW107337 antibody

G-6-Pase antibody

g6pc antibody

G6PT antibody

Glucose-6-phosphatase alpha antibody

GSD1 antibody

GSD1a antibody

MGC163350 antibody

MGC93613 antibody

RP23-281C18.19 antibody

General Information

Product

CMT Antibody

Description

Affinity Purified Protein-S-isoprenylcysteine O-methyltransferase Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 230-284 on human Protein-S-isoprenylcysteine O-methyltransferase.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

O60725

Overview

Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.

Molecular Function

Methyltransferase

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein

Expression

Ubiquitous

Structure

Belongs to class VI-like SAM-bidning methyltransferase superfamily.  Isoprenylcysteine carboxyl methyltransferase family

Alternative Nomenclature

fcmt 

HSTE14 

Icmt 

Isoprenylcysteine carboxylmethyltransferase 

MST098 

pcCMT 

Prenylcysteine carboxyl methyltransferase 

Protein-S-isoprenylcysteine O-methyltransferase 

STE14