General Information

Product

PREX1 Antibody

Description

Affinity Purified Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide corresponding to aino acid region 815-836 of Human PREX1. Peptide was covalently modified.

Sequence:

QEEDQADSAFPLLSLGPRLSLC

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.6 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Western Blot

1:500-1:750

Protein

Uniprot #

Q8TCU6

Overview

Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.

Molecular Function

enzyme binding, Rho GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding

Subcellular Location

Cytoplasm, cell membrane

Expression

Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues.

Alternative Nomenclature

4 antibody

5)-dependent Rac exchanger 1 antibody

P REX1 antibody

PtdIns(3,4,5) dependent Rac exchanger 1 antibody

SET domain containing 6 antibody

Setd6 antibody

General Information

Product

SIDT1 Antibody Affinity Purified

Description

Affinity Purified SIDT1 protein Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Rat, Mouse

Immunogen

Synthetic peptide taken within amino acid region 390-430 on human SIDT1 protein.

Accession #

Gen Bank: AAI17223.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61-0.63 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9NXL6

Molecular Function

RNA transmembrane transporter activity

Subcellular Location

membrane, multi-pass membrane protein

Alternative Nomenclature

Msid2 antibody

SID1 antibody

SID1 transmembrane family, member 1 antibody

General Information

Product

SPNS2 Antibody

Description

Affinity Purified Spingolipid transporter 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

D. melanogaster, Monkey, Mouse, Rat

Immunogen

Synthetic amidated peptide from Human SPNS2 protein, the epitope location is extracytoplasmic between TMD9 and TMD10.

Human, Mouse: amino acids 482-499

D. melanogaster: amino acids 373-389

The peptide was synthesized at 90% HPLC purity, covalently modifed to achieve the desired antigenicity, and conjugated to carrier proteins.

Sequence:

ISD LIR QST KDS PLW EF

Accession #

GenBank:  AAH41772 

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q8IVW8

Overview

Sphingolipid transporter required for migration of myocardial precursors.

Molecular Function

sphingolipid transporter activity

Subcellular Location

Membrane

Expression

esophagus,kidney,lung,gall bladder

Structure

Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.

Alternative Nomenclature

Protein spinster homolog 2 antibody

Spinster homolog 2 (Drosophila) antibody

SPNS 2 antibody

Spingolipid protein transporter 2 antibody

General Information

Product

TDRKH Antibody

Description

Affinity Purified Tudor and KH domain-containing protein (TDRKH) Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 480-515 on TDRD2 protein.

Accession #

Gen Bank: AF227192.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.56-0.58 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Dot Blot

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9Y2W6

Overview

Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons.

Molecular Function

RNA binding

Subcellular Location

cytoplasm, mitochondrion

Alternative Nomenclature

2700091C21Rik antibody

Putative RNA binding protein antibody

RGD1311196 antibody

RP11-98D18.8 antibody

TDRD2 antibody

TDRD7 antibody

Tudor and KH domain-containing protein antibody

Tudor domain-containing protein 2 antibody

General Information

Product

TM6SF1 Antibody

Description

Affinity Purified Transmembrane 6 superfamily member 1 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 320-370 on human TM6SF1 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.56 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9BZW5

Subcellular Location

membrane, multi-pass membrane protein

Expression

Enhanced expression in spleen, testis and peripheral blood leukocytes.

Alternative Nomenclature

Transmembrane 6 superfamily member 1 antibody

General Information

Product

VKORC1 Antibody

Description

Vitamin K epoxide reductase complex subunit 1 Antibody

Verified Applications

ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 10-60 on human VKORC1 protein.

Accession #

GenBank: AJE63371.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.70 µg/µl in antibody stabilization buffer

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

DB

1:50,000

ELISA

1:50,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q6TEK4

Overview

Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development.

Molecular Function

Oxidoreductase, Quinone binding, vitamin-K-epoxide reductase

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein

Expression

Highly expressed in liver. Detected at lower levels in lung, kidney and testis.

Alternative Nomenclature

3-epoxide reductase subunit 1 antibody

EDTP308 antibody

FLJ00289 antibody

IMAGE3455200 antibody

MGC2694 antibody

MST134 antibody

MST576 antibody

Phylloquinone epoxide reductase antibody

Vitamin K dependent clotting factors deficiency 2 antibody

Vitamin K epoxide reductase complex subunit 1 antibody

Vitamin K1 2 antibody

Vitamin K1 epoxide reductase (warfarin sensitive) antibody

VKCFD2 antibody

VKOR antibody

VKORC1 antibody

General Information

Product

C1orf146 Antibody

Description

Affinity Purified Chromosome 1 open reading frame 146 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 100-180 on human C1orf146 protein.

Accession #

NCBI:  NP_001012425

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68-0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q5VVC0

Overview

Uncharacterized protein C1orf146

Alternative Nomenclature

C1orf146 antibody

CA146_HUMAN antibody

Chromosome 1 open reading frame 146 antibody

RP11-163M2.4 antibody

Uncharacterized protein C1orf146 antibody

General Information

Product

Glucose Transporter GLUT3 Antibody

Description

Affinity Purified Solute carrier family 2, facilitated glucose transporter member 3 Antibody

Verified Applications

CM, ELISA, Flow cytometry, ICC/IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 400-493 on mouse SLC2A3 protein.

Accession #

NCBI: NP_008862

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confotcal Microscopy

1:250

DOT Blot

1:25,000

ELISA

1:25,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Immunoprecipitation

1:200

Western Blot

1:8,000

Protein

Uniprot #

Q4FJP8

Overview

Facilitative glucose transporter.

Molecular Function

Sugar Transport

Subcellular Location

Membrane; Multi-pass membrane protein

Expression

Brain and many other tissues.

Structure

Transmembrane helix

Alternative Nomenclature

brain antibody

FLJ90380 antibody

Glucose transporter type 3 brain antibody

GLUT-3 antibody

SLC2A3 antibody

Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 3 antibody

General Information

Product

FNDC5 Antibody

Description

Affinity Purified Fibronectin type III domain-containing protein 5 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequences on human FNDC5 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q8K4Z2

Overview

Irisin: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA.

Molecular Function

Hormone

Subcellular Location

Cell membrane, Membrane, Peroxisome, Secreted

Expression

highly expressed in skeletal muscle, heart and brain.

Alternative Nomenclature

Fibronectin type III domain containing 5 antibody

FNDC 5 antibody

FRCP2 antibody

irisin antibody

General Information

Product

PAR1 Antibody

Description

Affinity Purified Proteinase-activated receptor 1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 390-440 on mouse PAR1 protein.

Accession #

NCBI:  NP_034299.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.63-0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:250

Protein

Uniprot #

P30558

Overview

Functions as a high affinity receptor for activated thrombin coupled to G proteins that serve to  stimulate hydrolysis.

Alternative Nomenclature

CF2R antibody

Coagulation factor II (thrombin) receptor antibody

F2R antibody

HTR antibody

PAR 1 antibody

Protease activated receptor 1 antibody

Thrombin receptor antibody

TR antibody