General Information

Product

PAR2 Antibody

Description

Affinity Purified Proteinase-activated receptor 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Chimpanzee, Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 300-370 of mouse PAR2.

Accession #

NCBI:  NP_032000.3

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.62 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:15,00-1:20,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:250

Protein

Uniprot #

P55086

Overview

Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.

Structure

Interacts with TLR4, COPS5 and TMED2.  Also interacts with GNAQ, GNA11, GNA12, GNA13, and GNA14.

Alternative Nomenclature

Coagulation factor II receptor like 1 

Coagulation factor II thrombin receptor like 1

F2RL1 

G protein coupled receptor 11 

GPR11 

PAR 2 

Proteinase activated receptor 2

Thrombin receptor like 1 

General Information

Product

PREX2 Antibody Affinity Purified

Description

Affinity Purified PtdIns(3,4,5)-dependent Rac exchanger 2a Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse

Immunogen

Synthetic peptide taken within amino acid region 720-900 on PREX2 protein.

Accession #

GenBank:  DAA05334.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Western Blot

1:500-1:750

Protein

Uniprot #

Q70Z35

Overview

Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.

Molecular Function

Rac GTPase activator activity, Rac guanyl-nucleotide exchange factor activity

Expression

Isoform 1 is highly expressed in skeletal muscle, heart and placenta, absent from peripheral blood leukocytes. Isoform 2 is expressed in skeletal muscle, kidney, small intestine, and placenta. Isoform 3 is expressed in the heart.

Alternative Nomenclature

4 antibody

5)-dependent Rac exchanger 2 antibody

5-trisphosphate-dependent Rac exchanger 2 protein antibody

DEP domain-containing protein 2 antibody

DEP.2 antibody

Phosphatidylinositol 3 antibody

PtdIns(3,4,5)-dependent Rac exchanger 2 antibody

General Information

Product

Baboon Antibody

Description

Affinity Purified Baboon Antibody N-epitope

Verified Applications

ELISA, ICC/IF, IP, WB

Species Cross Reactivity

D. melanogaster

Immunogen

N-epitope Synthetic peptide corresponding to amino acid region 200-221 of Drosophila melanogaster protein. The peptide was covalently modified for conjugation.

Synthetic peptide:

CNKNENMKRIFEDYVPHRLTS

Accession #

GenBank:  U04692

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.6 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500. Predicted molecular weight: 73 kDa

Protein

Uniprot #

Q23975

Overview

Invovled in activin binding, GPCR kinase activity, serine threonine kinase activity and transforming growth factor beta receptor activity.

Molecular Function

Serine/threonine protein kinase; transferase; ATP and Nucleotide binding

Subcellular Location

Activin receptor complex; Membrane

Structure

Belongs to protein kinase superfamily and contains protein kinase domain.

Alternative Nomenclature

Activin A receptor 45A antibody

ATR1 antibody

Atr45A antibody

Bab antibody

Babo antibody

G protein coupled receptor kinase 3 antibody

Gprk3 antibody

STKE antibody

General Information

Product

Baboon Antibody

Description

Affinity Purified Baboon Antibody C-epitope

Verified Applications

ELISA, ICC/IF, IHC, IP, WB

Immunogen

C-epitope Synthetic peptide corresponding to amino acids 552-572 of Drosophila melanogaster Baboon protein. Peptide was covalently modified.

Sequence:

QPDPSIEEMKKVVCIEKCRPN

Accession #

GenBank:  U04692

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.66 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q23975

Overview

Invovled in activin binding, GPCR kinase activity, serine threonine kinase activity and transforming growth factor beta receptor activity.

Molecular Function

Serine/threonine protein kinase; transferase; ATP and Nucleotide binding

Subcellular Location

Activin receptor complex; Membrane

Structure

Belongs to protein kinase superfamily and contains protein kinase domain.

Alternative Nomenclature

Activin A receptor 45A antibody

ATR1 antibody

Atr45A antibody

Bab antibody

Babo antibody

G protein coupled receptor kinase 3 antibody

Gprk3 antibody

STKE antibody

General Information

Product

C2orf88 Antibody Affinity Purified

Description

Affinity Purified Small membrane A-kinase anchor protein Antibody N-epitope

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

N-epitope synthetic peptide taken within amino acid region 1-50 on human C2orf88 protein.

Accession #

NCBI: NP_115697.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.7 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:15,000-1:20,000

ELISA

1:15,000-1:20,000

Western Blot

1:500

Protein

Uniprot #

Q9BSF0

Overview

Binds to type I regulatory subunits of protein kinase A (PKA-RI) and may anchor/target them to the plasma membrane

Subcellular Location

Cell membrane, Membrane

Expression

Expressed in heart (at protein level)

Alternative Nomenclature

Chromosome 2 open reading frame 88 antibody

MGC13057 antibody

Uncharacterized protein FLJ90687 antibody

UPF0733 protein C2orf88 antibody

General Information

Product

C2orf88 Antibody Affinity Purified

Description

Affinity Purified Small membrane A-kinase anchor protein Antibody Mid-Region

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Mid Region epitope synthetic peptide taken within amino acid region 25-100 on human C2orf88 protein.

Accession #

NCBI: NP_115697.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.7 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid-Region

Storage

-20⁰C for long term storage

Application Protocol

DB

1:15,000-1:20,000

ELISA

1:15,000-1:20,000

Western Blot

1:500

Protein

Uniprot #

Q9BSF0

Overview

Binds to type I regulatory subunits of protein kinase A (PKA-RI) and may anchor/target them to the plasma membrane

Subcellular Location

Cell membrane, Membrane

Expression

Expressed in heart (at protein level)

Alternative Nomenclature

Chromosome 2 open reading frame 88 antibody

MGC13057 antibody

Uncharacterized protein FLJ90687 antibody

UPF0733 protein C2orf88 antibody

General Information

Product

C2orf88 Antibody Affinity Purified

Description

Affinity Purified Small membrane A-kinase anchor protein Antibody C-epitope

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

C-epitope synthetic peptide taken within amino acid region 50-100 on human C2orf88 protein.

Accession #

NCBI: NP_115697.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.7 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:15,000-1:20,000

ELISA

1:15,000-1:20,000

Western Blot

1:500

Protein

Uniprot #

Q9BSF0

Overview

Binds to type I regulatory subunits of protein kinase A (PKA-RI) and may anchor/target them to the plasma membrane

Subcellular Location

Cell membrane, Membrane

Expression

Expressed in heart (at protein level)

Alternative Nomenclature

Chromosome 2 open reading frame 88 antibody

MGC13057 antibody

Uncharacterized protein FLJ90687 antibody

UPF0733 protein C2orf88 antibody

General Information

Product

Disembodied Antibody Affinity Purified

Description

Affinity Purified Cytochrome P450 302a1, mitochondrial Antibody N-epitope

Verified Applications

CM, ELISA, ICC, IF, WB

Host

Rabbit

Species Cross Reactivity

D. melanogaster

Immunogen

Synthetic peptide corresponding to unique sequence on Disemboided protein.

Accession #

NCBI: AAF60174.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75-1.2 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20°C for long term storage

Application Protocol

Confocal Microscopy

1:250

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Western Blot

1:500

Protein

Uniprot #

Q9NGX9

Overview

Negatively regulates glial cell division in the embryonic midline.  Invovled in metabolism of insect hormones.

Molecular Function

Steroid biosynthesis; ecdysteroid biosynthesis

Subcellular Location

Mitochondrion membrane

Expression

Complex coexpression of disembodied and shade in early embryo that restricts to the prothracic gland cells of developing ring gland during late embryogenesis.

Structure

Belongs to cytochrome P450 family

Alternative Nomenclature

dib Antibody

General Information

Product

Disembodied Antibody Affinity Purified

Description

Affinity Purified Cytochrome P450 302a1, mitochondrial Antibody

Verified Applications

CM, ELISA, ICC, IF, WB

Host

Rabbit

Species Cross Reactivity

D. melanogaster

Immunogen

Synthetic peptide corresponding to unique sequence on Disemboided protein.

Accession #

NCBI: AAF60174.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75-1.2 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20°C for long term storage

Application Protocol

Confocal Microscopy

1:250

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Western Blot

1:500

Protein

Uniprot #

Q9NGX9

Overview

Negatively regulates glial cell division in the embryonic midline.  Invovled in metabolism of insect hormones.

Molecular Function

Steroid biosynthesis; ecdysteroid biosynthesis

Subcellular Location

Mitochondrion membrane

Expression

Complex coexpression of disembodied and shade in early embryo that restricts to the prothracic gland cells of developing ring gland during late embryogenesis.

Structure

Belongs to cytochrome P450 family

Alternative Nomenclature

dib Antibody

General Information

Product

C11orf1 Antibody Affinity Purified

Description

Affinity Purified Chromosome 11 open reading frame 1 Antibody N-epitope

Verified Applications

ELISA

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human C11orf1 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.67 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:15,000-1:20,000

ELISA

1:15,000-1:20,000

Protein

Uniprot #

Q9H5F2

Molecular Function

Nucleus

Alternative Nomenclature

C11orf1 antibody

Chromosome 11 open reading frame 1 antibody

UPF0686 protein