General Information |
|
Product |
VPS26 Peptide |
Description |
Antigenic Blocking Peptide Vacuolar protein sorting-associated protein 26A |
Verified Applications |
Immunocompetition, Immunodepletion |
Peptide Description |
Synthetic peptide taken within amino acids 315-375 on human VPS26 protein. |
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|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
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|
Competition/Depletion assay |
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|
|
Uniprot # |
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Overview |
Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. |
Molecular Function |
protein transporter activity |
Subcellular Location |
cytoplasm, endosome membrane, preipheral membrane protein (Note: Localizes to tubular profiles adjacent to endosomes. Predominantly found in early not late endosomes) |
Expression |
Down-regulated in Alzheimer disease. No polymorphism or variant is however associated with Alzheimer disease for VPS26A. |
Alternative Nomenclature |
FLJ12930 antibody FLJ12930 antibody HB 58 antibody Hbeta 58 antibody Hbeta 58 homolog antibody MGC94168 antibody PEP 8A antibody Vacuolar protein sorting 26 A antibody Vacuolar protein sorting 26 homolog A yeast antibody Vacuolar protein sorting associated protein 26A antibody Vesicle protein sorting 26A antibody VPS 26 antibody VPS 26A antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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VPS26-101AP | |||
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VPS26-FITC | |||
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VPS26-BIOTIN | |||
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PC-VPS26 | |||
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