General Information
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Product
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SOX2 Positive Control
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Description
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Western Blot Positive Control Sex determing region Y-box 2
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Verified Applications
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WB
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Immunogen
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Purified Protein
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Accession #
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GenBank: AJF45879.1
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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Storage
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-20⁰C for long term storage
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Application Protocol
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Western Blot
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1:500
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Protein
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Uniprot #
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A0A0B5HSU3
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Overview
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Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation.
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Molecular Function
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Chromatin binding; DNA binding; miRNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription.
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Subcellular Location
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Nucleus
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Structure
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Interacts with ZSCAN10. Interacts with SOX3 and FGFR1.
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Alternative Nomenclature
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ANOP3 antibody
cb236 antibody
Delta EF2a antibody
lcc antibody
MCOPS3 antibody
MGC148683 antibody
MGC2413 antibody
RGD1565646 antibody
SRY (sex determining region Y) box 2 antibody
SRY box containing gene 2 antibody
SRY related HMG box gene 2 antibody
SRY-box 2 antibody
Transcription factor SOX 2 antibody
ysb antibody
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