General Information |
|
Product |
PREX2 Antibody FITC-Conjugated |
Description |
FITC-Conjugated PtdIns(3,4,5)-dependent Rac exchanger 2a Antibody |
Verified Applications |
ELISA, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse |
Immunogen |
Synthetic peptide taken within amino acid region 720-900 on PREX2 protein. |
Accession # |
GenBank: DAA05334.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.65 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:20,000-1:50,000 |
ELISA |
1:20,000-1:50,000 |
Western Blot |
1:500-1:750 |
|
|
Uniprot # |
|
Overview |
Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase. |
Molecular Function |
Rac GTPase activator activity, Rac guanyl-nucleotide exchange factor activity |
Expression |
Isoform 1 is highly expressed in skeletal muscle, heart and placenta, absent from peripheral blood leukocytes. Isoform 2 is expressed in skeletal muscle, kidney, small intestine, and placenta. Isoform 3 is expressed in the heart. |
Alternative Nomenclature |
4 antibody 5)-dependent Rac exchanger 2 antibody 5-trisphosphate-dependent Rac exchanger 2 protein antibody DEP domain-containing protein 2 antibody DEP.2 antibody Phosphatidylinositol 3 antibody PtdIns(3,4,5)-dependent Rac exchanger 2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
PREX2-201AP | |||
|
P-PREX2 | |||
|
PREX2-BIOTIN | |||
|
PC-PREX2 | |||
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