General Information
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Product
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Aquaporin 4 Peptide
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 300-323 on rat Aquaporin 4 protein.
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Accession #
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NCBI: NP_001641
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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P55087
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Overview
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Forms water specific channel. Osmoreceptor which regulates water balance and mediates water flow within CNS.
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Molecular Function
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Transport
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Subcellular Location
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Membrane; Multi-pass protein
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Expression
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Abundant in mature brain but only weakly detectable in eye, kidney, intestine, and lung.
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Structure
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Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
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Alternative Nomenclature
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AQP 4 antibody
Aquaporin type 4 antibody
Aquaporin-4 antibody
HMIWC2 antibody
Mercurial insensitive water channel antibody
MGC22454 antibody
MIWC antibody
WCH 4 antibody
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