14-3-3 sigma Antibody

Product no.: SFN-101AP
$285.00


General Information

 

 

Product

 

14-3-3 sigma Antibody

Description

Affinity Purified 14-3-3 protein sigma / STRATIFIN / SFN Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 150-220 on human 14-3-3 protein sigma / STRATIFIN / SFN protein.


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

 

ELISA

 

1:50,000

Immunohistochemistry 1:50-1:200

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000


Protein

 

Uniprot #

 

P31947

Overview

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.1 Publication

p53-regulated inhibitor of G2/M progression.

Molecular Function

cadherin binding

identical protein binding

phosphoprotein binding

protein domain specific binding

protein kinase binding

protein kinase C inhibitor activity

Subcellular Location

Nucleus, secreted

Expression

Present mainly in tissues enriched in stratified squamous keratinizing epithelium.

Structure

Belongs to the 14-3-3 family.

Alternative Nomenclature

14 3 3 protein sigma antibody

1433S_HUMAN antibody

Epithelial cell marker protein 1 antibody

Er antibody

HME 1 antibody

Mkrn3 antibody

Mme1 antibody

RP23 137L22.11 antibody

SFN antibody

SFN protein antibody

Stratifin antibody

YWHAS antibody

   

Protein information supplied by UniProt.

 

Accessories

Product Note Status Price
14-3-3 sigma Antibody BIOTIN 14-3-3 sigma Antibody BIOTIN
SFN-BIOTIN $375.00 *
14-3-3 sigma Antibody FITC 14-3-3 sigma Antibody FITC
SFN-FITC $375.00 *
14-3-3 sigma Blocking Peptide 14-3-3 sigma Blocking Peptide
P-SFN $155.00 *
14-3-3 sigma Positive Control 14-3-3 sigma Positive Control
PC-SFN $200.00 *
Display accessory details

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