General Information |
|
Product |
FBXW4 / SHFM3 Antibody FITC-Conjugated |
Description |
FITC-Conjugated F-box and WD-40 domain protein 4 Antibody |
Verified Applications |
DB, ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Monkey, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 240-290 on human FBX4 protein. |
Accession # |
GenBank: AAH07380.2 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.68-0.7 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:4,000 |
ELISA |
1:4,000 |
Immunoprecipitation |
1:150 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling. |
Molecular Function |
Developmental Protein |
Subcellular Location |
Ubiquitin ligase complex |
Expression |
Expressed in brain, kidney, lung and liver. |
Structure |
Part of a SCF (SKP1-cullin-F-box) protein ligase complex |
Alternative Nomenclature |
DAC antibody Dactylin antibody F box and WD 40 domain containing protein 4 antibody F box/WD repeat protein 4 antibody F-box/WD repeat-containing protein 4 antibody FBW 4 antibody FBWD4 antibody SHFM 3 antibody SHSF3 antibody Split hand/foot malformation (ectrodactyly) type antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
FBXW4-401AP | |||
|
P-FBXW4 | |||
|
FBXW4-BIOTIN | |||
|
PC-FBXW4 | |||
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