CXCR2 Antibody

Product no.: CXCR2-201AP

General Information
Product	CXCR2 Antibody
Verified Applications	CM, ELISA, ICC/IF, IHC-Fr, IHC-P, IP, FC, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide: EDLSNYSYSSTLPPFLLDAAPC Corresponding to amino acids 18-39 of Human CXCR2.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Isotype	IgG
Determinant	N-epitope
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:200
DB	1:10,000
ELISA	1:10,000
Immunocytochemistry	1:200
Immunofluorescence	1:200
Immunohistochemistry	1:200
Immunoprecipitation	1:250
Western Blot	1:500 Predicted molecular weight: 55 kDa
Protein
Uniprot #	P25025
Overview	Receptor for interleukin-8, binding of IL-8 to the receptor causes the activation of neutrophils. This response is mediated by a G-protein which activates a phosphatidyinositol-calcium second messenger system.
Molecular Function	G-Protein coupled receptor, Transducer, chemokine receptor activity
Subcellular Location	Cell membrane; Multi-pass membrane protein
Expression	Up-regulated by CREB3
Structure	Binds to HIV-1 Tat and interacts with ARRB1
Alternative Nomenclature	C-X-C chemokine receptor type 2 antibody CD 182 antibody CD182 antigen antibody CDw128b antibody Chemokine (CXC) receptor 2 antibody CMKAR2 antibody CXCR2 antibody GRO/MGSA receptor antibody High affinity interleukin-8 receptor B antibody IL8R B antibody IL8R2 antibody IL8RA antibody Interleukin 8 receptor, beta antibody Interleukin 8 receptor, type 2 antibody

Protein information supplied by UniProt

Fabgennix CXCR2 Antibody has been used in 2 Publications

Sun, Jia, Raina Devi Ramnath, and Madhav Bhatia. "Neuropeptide substance P upregulates chemokine and chemokine receptor expression in primary mouse neutrophils." American Journal of Physiology-Cell Physiology 293.2 (2007): C696-C704. PMID17494633

Flow Cytometry; Mouse

Zhang, Huili, et al. "Endogenous hydrogen sulfide regulates leukocyte trafficking in cecal ligation and puncture-induced sepsis." Journal of leukocyte biology 82.4 (2007): 894-905.
APA PMID17599903

Flow Cytometry; Mouse

Publishing research using CXCR2-201AP? Please let us know, we can cite the reference in this datasheet.

To view the Specification Sheet for CXCR2 Antibody, please click the link below:

CXCR2 Antibody | FabGennix

Customer ratings for CXCR2 Antibody

Number of ratings: 2
Average rating: 4.5

Good
from Verified Customer on 12/09/2020

Good in Immunocytochemistry/ Immunofluorescence using Human cells (PC3 Prostate cancer cells). 1:100 incubation in PBS for 1 hour.

Excellent
from Anonymous on 11/13/2015

Immunocytochemistry/Immunofluorescence
Mouse Spleen Smear Paraformaldehyde
Serum as locking agent for 1 hour at room temperature
1:200 antibody dilution in PBS for 1 hour

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