AIM2 Antibody

Catalog no. AIM2-201AP · Research Use Only

$285 per 100 µg. Ships within 2–3 business days from the U.S.

AIM2-201AP — affinity purified Rabbit antibody against AIM2. Validated for ELISA, IHC, IP, WB. Reacts with Human, Mouse.

Specifications

Catalog numberAIM2-201AP
TargetAIM2
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ReactivityHuman, Mouse
ApplicationsELISA, IHC, IP, WB
ConjugateUnconjugated
PurityAffinity Purified
ImmunogenSynthetic peptide taken within amino acid region 240-340 on human AIM2 protein.
Size100 µg
Storage-20°C
UniProtO14862

About this target

Innate immune response recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity. Self-associates; forms homodimers in response to cytosolic dsDNA and the dsDNA serves as oligomerization platform. Expression: Expressed in spleen, small intestine, peripheral blood leukocytes and testis.

Documents

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.