Amyloid Precursor Protein Blocking Peptide

Catalog no. P-BAPPA4 · Research Use Only

$155 per 250 µg. Ships within 2–3 business days from the U.S.

P-BAPPA4 — affinity-purified Rabbit antibody against Amyloid Precursor Protein. Validated for Immunodepletion, Immunocompetition.

Specifications

Catalog numberP-BAPPA4
TargetAmyloid Precursor Protein
ApplicationsImmunodepletion, Immunocompetition
ConjugateUnconjugated
ImmunogenSynthetic peptide corresponding to amino acids within region 700-770 on human BAPPA4 protein.
Size250 µg
Storage-20°C
UniProtP05067

About this target

Amyloid Precursor Protein Blocking Peptide is the antigenic blocking peptide for the Amyloid Precursor Protein antibody BAPPA4-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(o) and JIP. Inhibits G(o) alpha ATPase activity. Subcellular location: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Perikaryon. Cell projection, growth cone. Membrane, clathrin-coated pit. Early endosome. Cytoplasmic vesicle.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.