Androgen Receptor Blocking Peptide
Catalog no. P-ANDR · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-ANDR — affinity-purified Rabbit antibody against Androgen Receptor. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-ANDR |
|---|---|
| Target | Androgen Receptor |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide corresponding to amino acids within region 550-600 on Human Androgen Receptor. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | P10275 |
About this target
Androgen Receptor Blocking Peptide is the antigenic blocking peptide for the Androgen Receptor antibody ANDR-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Subcellular location: Nucleus. Cytoplasm. Note=Detected at the promoter of target genes. Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RACK1.
Documents
Related products
- Androgen Receptor Antibody (ANDR-101AP)
- Androgen Receptor Antibody BIOTIN (ANDR-BIOTIN)
- Androgen Receptor Antibody FITC (ANDR-FITC)
- Androgen Receptor Positive Control (PC-ANDR)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.