TLR1 Antibody
Catalog no. TLR-112AP · Research Use Only
$285 per 100 µg. Ships within 2–3 business days from the U.S.
TLR-112AP — affinity purified Rabbit antibody against TLR1. Validated for ELISA, IHC, IP, WB. Reacts with Human, Mouse, Rat.
Specifications
| Catalog number | TLR-112AP |
|---|---|
| Target | TLR1 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC, IP, WB |
| Conjugate | Unconjugated |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide taken within amino acid region 370-420 on human Toll-like receptor 1. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | Q15399 |
About this target
Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Binds MYD88 (via TIR domains) (By similarity). Interacts (via extracellular domain) with TLR2. Ligand binding induces the formation of a heterodimer with TLR2 (By similarity). Interacts with CNPY3. Subcellular location: Cell membrane; Single-pass type I membrane protein, Cytoplasmic vesicle > phagosome membrane; Single-pass type I membrane protein.
Documents
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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.