BMP2 Blocking Peptide
Catalog no. P-BMP-212 · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-BMP-212 — affinity-purified Rabbit antibody against BMP2. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-BMP-212 |
|---|---|
| Target | BMP2 |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide corresponding to amino acids within region 340-396 on human Bone morphogenetic Protein 2. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | P12643 |
About this target
BMP2 Blocking Peptide is the antigenic blocking peptide for the BMP2 antibody BMP-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cardiogenesis, neurogenesis, and osteogenesis. Induces cartilage and bone formation. Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. Once all three components are bound together in a complex at the cell surface, BMPR2 phosphorylates and activates BMPR1A. In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes. Subcellular location: Secreted.
Documents
Related products
- BMP2 Antibody (BMP-201AP)
- BMP2 Antibody BIOTIN (BMP-212-BIOTIN)
- BMP2 Antibody FITC (BMP-212-FITC)
- BMP2 Antibody (BMP-212AP)
- BMP2 Antibody BIOTIN (BMP2-BIOTIN)
- BMP2 Antibody FITC (BMP2-FITC)
- BMP2 Blocking Peptide (P-BMP2)
- BMP2 Positive Control (PC-BMP2)
- BMP2 Positive Control (PC-BMP2-212)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.