CD16a Blocking Peptide
Catalog no. P-CD16A · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-CD16A — affinity-purified Rabbit antibody against CD16a. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-CD16A |
|---|---|
| Target | CD16a |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide taken within amino acid region 205-254 on CD16a protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | P08637 |
About this target
CD16a Blocking Peptide is the antigenic blocking peptide for the CD16a antibody CD16A-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG). Optimally activated upon binding of clustered antigen-IgG complexes displayed on cell surfaces, triggers lysis of antibody-coated cells, a process known as antibody-dependent cellular cytotoxicity (ADCC). Does not bind free monomeric IgG, thus avoiding inappropriate effector cell activation in the absence of antigenic trigger. Mediates IgG effector functions on natural killer (NK) cells. Binds antigen-IgG complexes generated upon infection and triggers NK cell-dependent cytokine production and degranulation to limit viral load and propagation. Subcellular location: Cell membrane; Single-pass type I membrane protein. Secreted. Note=Also exists as a soluble receptor.
Documents
Related products
- CD16a Antibody (CD16A-101AP)
- CD16a Antibody BIOTIN (CD16A-BIOTIN)
- CD16a Antibody FITC (CD16A-FITC)
- CD16a Antibody Positve Control (PC-CD16A)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.