DWORF Blocking Peptide
Catalog no. P-DWORF-112 · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-DWORF-112 — affinity-purified Rabbit antibody against DWORF. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-DWORF-112 |
|---|---|
| Target | DWORF |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synththetic peptide corresponding to full length Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | P0DN83 |
About this target
DWORF Blocking Peptide is the antigenic blocking peptide for the DWORF antibody DWORF-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Enhances the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by displacing ATP2A1/SERCA1 inhibitors, thereby acting as a key regulator of skeletal muscle activity. Also enhances the activity of the ATP2A2/SERCA2 ATPase. Does not directly stimulate SERCA pump activity. Binds preferentially to the phosphorylated E1 and E2 conformational forms of ATP2A2 which predominate at high Ca(2+) concentrations during the systolic phase of the cardiac cycle. Competes with ATP2A2 inhibitor phospholamban (PLN) for binding to ATP2A2 and displaces PLN. Can activate ATP2A2 directly in the absence of PLN. Subcellular location: Sarcoplasmic reticulum membrane; Single-pass membrane protein.
Documents
Related products
- DWORF Antibody (DWORF-101AP)
- DWORF Antibody BIOTIN (DWORF-112-BIOTIN)
- DWORF Antibody FITC (DWORF-112-FITC)
- DWORF Antibody (DWORF-112AP)
- DWORF Antibody BIOTIN (DWORF-BIOTIN)
- DWORF Antibody FITC (DWORF-FITC)
- DWORF Blocking Peptide (P-DWORF)
- DWORF Positive Control (PC-DWORF)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.