Filamin B (phospho 2478) Antibody
Catalog no. PFLNB-140AP · Research Use Only
$375 per 100 µg. Ships within 2–3 business days from the U.S.
PFLNB-140AP — affinity purified Rabbit antibody against Filamin B (phospho 2478). Validated for ELISA, IP, WB. Reacts with Human, Mouse.
Specifications
| Catalog number | PFLNB-140AP |
|---|---|
| Target | Filamin B (phospho 2478) |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse |
| Applications | ELISA, IP, WB |
| Conjugate | Unconjugated |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide taken within amino acid region 2450-2500 on human Phospho-Filamin-B. Phosphorylated 2478 serine residue. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | O75369 |
About this target
Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton. Interaction with FLNA. Homodimer. Interacts with MICALL2 (By similarity). Interacts with RFLNA and RFLNB (By similarity). Isoform 1 interacts with FBLP1, FLNA, FLNC, GP1BA, INPPL1, ITGB1A, PSEN1 and PSEN2. Isoform 3 interacts with ITGB1A, ITGB1D, ITGB3 and ITGB6. Interacts with. Subcellular location: Cytoskeleton. Expression: Ubiquitous. Isoform 1 and isoform 2 are expressed in placenta, bone marrow, brain, umbilical vein endothelial cells (HUVEC), retina and skeletal muscle. Isoform 1 is predominantly expressed in prostate, uterus, liver, thyroid, stomach, lymph node, small i.
Documents
Related products
- Filamin B (phospho 2478) Blocking Peptide (P-PFLNB)
- Filamin B (phospho 2478) Positive Control (PC-PFLNB)
- Filamin B (phospho 2478) Antibody BIOTIN (PFLNB-BIOTIN)
- Filamin B (phospho 2478) Antibody FITC (PFLNB-FITC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.