Filamin B (phospho 2481) Antibody BIOTIN

Catalog no. PFLNB-240-BIOTIN · Research Use Only

$425 per 100 µg. Ships within 2–3 business days from the U.S.

PFLNB-240-BIOTIN — affinity purified Rabbit antibody against Filamin B (phospho 2481). Validated for ELISA, IP, WB. Reacts with Human, Mouse.

Specifications

Catalog numberPFLNB-240-BIOTIN
TargetFilamin B (phospho 2481)
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ReactivityHuman, Mouse
ApplicationsELISA, IP, WB
ConjugateBIOTIN
PurityAffinity Purified
ImmunogenSynthetic peptide taken within amino acid region 2450-2500 on human Phospho-Filamin-B. Phosphorylated 2481 serine residue.
Size100 µg
Storage-20°C
UniProtO75369

About this target

Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton. Interaction with FLNA. Homodimer. Interacts with MICALL2 (By similarity). Interacts with RFLNA and RFLNB (By similarity). Isoform 1 interacts with FBLP1, FLNA, FLNC, GP1BA, INPPL1, ITGB1A, PSEN1 and PSEN2. Isoform 3 interacts with ITGB1A, ITGB1D, ITGB3 and ITGB6. Interacts with. Subcellular location: Cytoskeleton. Expression: Ubiquitous. Isoform 1 and isoform 2 are expressed in placenta, bone marrow, brain, umbilical vein endothelial cells (HUVEC), retina and skeletal muscle. Isoform 1 is predominantly expressed in prostate, uterus, liver, thyroid, stomach, lymph node, small i.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.