GPC-3 Antibody BIOTIN
Catalog no. GPC3-BIOTIN · Research Use Only
$375 per 100 µg. Ships within 2–3 business days from the U.S.
GPC3-BIOTIN — affinity purified Rabbit antibody against Glypican 3. Validated for ELISA, WB. Reacts with Human, Mouse, Rat.
Specifications
| Catalog number | GPC3-BIOTIN |
|---|---|
| Target | Glypican 3 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, WB |
| Conjugate | BIOTIN |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide taken within amino acid region 195-244 on GPC-3 protein. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | P51654 |
About this target
GPC-3 Antibody BIOTIN is the biotin-conjugated version of the Glypican 3 antibody GPC3-101AP, an affinity-purified rabbit polyclonal used in ELISA, WB and reactive with Human, Mouse, Rat. The conjugate removes the need for a labeled secondary antibody in direct detection. For research use only. Cell surface proteoglycan. Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins. Binding to the hedgehog protein SHH triggers internalization of the complex by endocytosis and its subsequent lysosomal degradation. Positively regulates the canonical Wnt signaling pathway by binding to the Wnt receptor Frizzled and stimulating the binding of the Frizzled receptor to Wnt ligands. Positively regulates the non-canonical Wnt signaling pathway. Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
Documents
Related products
- GPC-3 Antibody (GPC3-101AP)
- GPC-3 Antibody FITC (GPC3-FITC)
- GPC-3 Blocking Peptide (P-GPC3)
- GPC-3 Antibody Positve Control (PC-GPC3)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.