HLA-G Blocking Peptide
Catalog no. P-HLAG · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-HLAG — affinity-purified Rabbit antibody against HLA class I histocompatibility antigen, alpha chain G. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-HLAG |
|---|---|
| Target | HLA class I histocompatibility antigen, alpha chain G |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide taken within amino acid region 192-241 on HLA-G protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | P17693 |
About this target
HLA-G Blocking Peptide is the antigenic blocking peptide for the HLA class I histocompatibility antigen, alpha chain G antibody HLAG-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. [Isoform 1]: Non-classical major histocompatibility class Ib molecule involved in immune regulatory processes at the maternal-fetal interface. In complex with B2M/beta-2 microglobulin binds a limited repertoire of nonamer self-peptides derived from intracellular proteins including histones and ribosomal proteins. Peptide-bound HLA-G-B2M complex acts as a ligand for inhibitory/activating KIR2DL4, LILRB1 and LILRB2 receptors on uterine immune cells to promote fetal development while maintaining maternal-fetal tolerance. Subcellular location: [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane.
Documents
Related products
- HLA-G Antibody (HLAG-101AP)
- HLA-G Antibody BIOTIN (HLAG-BIOTIN)
- HLA-G Antibody FITC (HLAG-FITC)
- HLA-G Antibody Positve Control (PC-HLAG)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.