Humanin Blocking Peptide
Catalog no. P-HUMN-112 · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-HUMN-112 — affinity-purified Rabbit antibody against Humanin. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-HUMN-112 |
|---|---|
| Target | Humanin |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | Q8IVG9 |
About this target
Humanin Blocking Peptide is the antigenic blocking peptide for the Humanin antibody HUMN-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by binding to the humanin receptor complex; binding of MT-RNR2 activates the intracellular JAK-STAT3 signaling pathways. Also acts as a ligand for G protein-coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation. Subcellular location: Secreted. Cytoplasm. Cell projection, cilium, flagellum. Nucleus. Mitochondrion. Note=Localizes to the sperm flagellum where it is highly concentrated in the midpiece. Detected in the cytoplasm and nucleus of spermatocytes and spermatids.
Documents
Related products
- Humanin Antibody (HUMN-101AP)
- Humanin Antibody BIOTIN (HUMN-112-BIOTIN)
- Humanin Antibody FITC (HUMN-112-FITC)
- Humanin Antibody (HUMN-112AP)
- Humanin Antibody (HUMN-112Y)
- Humanin Antibody BIOTIN (HUMN-112Y-BIOTIN)
- Humanin Antibody FITC (HUMN-112Y-FITC)
- Humanin Antibody BIOTIN (HUMN-BIOTIN)
- Humanin Antibody FITC (HUMN-FITC)
- Humanin Blocking Peptide (P-HUMN)
- Humanin Blocking Peptide (P-HUMN-112Y)
- Humanin Positive Control (PC-HUMN)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.