IL18RAP Antibody

Catalog no. IL18RAP-101AP · Research Use Only

$285 per 100 µg. Ships within 2–3 business days from the U.S.

IL18RAP-101AP — affinity purified Rabbit antibody against IL18RAP. Validated for ELISA, IHC, IP, WB. Reacts with Human, Mouse, Rat.

Specifications

Catalog numberIL18RAP-101AP
TargetIL18RAP
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, IP, WB
ConjugateUnconjugated
PurityAffinity Purified
ImmunogenSynthetic peptide taken within amino acid region 500-550 on human Interleukin-18 receptor accessory protein.
Size100 µg
Storage-20°C
UniProtO95256

About this target

Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. Belongs to the interleukin-1 receptor family. Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 TIR domain. Subcellular location: Membrane, Single-pass type I membrane protein. Expression: Strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon, but not in any other tissue tested. Strongly expressed in T-cells polarized with IL-12. Specifically coexpressed with IL18R1 in Th1 cells.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.