Keap1 Positive Control
Catalog no. PC-KEAP1 · Research Use Only
$200 per 5 applications. Ships within 2–3 business days from the U.S.
PC-KEAP1 — affinity-purified Rabbit antibody against Keap1. Validated for WB.
Specifications
| Catalog number | PC-KEAP1 |
|---|---|
| Target | Keap1 |
| Applications | WB |
| Conjugate | Unconjugated |
| Immunogen | Partially purified human Kelch-like ECH-associated protein 1 protein. |
| Size | 5 applications |
| Storage | -20°C |
| UniProt | Q14145 |
About this target
Keap1 Positive Control is a Western blot positive control for Keap1 antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting NFE2L2/NRF2 for ubiquitination. KEAP1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of NFE2L2/NRF2, a transcription factor regulating expression of many cytoprotective genes. Subcellular location: Cytoplasm. Nucleus. Note=Mainly cytoplasmic. In response to selective autophagy, relocalizes to inclusion bodies following interaction with SQSTM1/p62.
Documents
Related products
- Keap1 Antibody (KEAP1-101AP)
- Keap1 Antibody BIOTIN (KEAP1-BIOTIN)
- Keap1 Antibody FITC (KEAP1-FITC)
- Keap1 Blocking Peptide (P-KEAP1)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.