Legumain Antibody BIOTIN

Catalog no. LGMN-BIOTIN · Research Use Only

$375 per 100 µg. Ships within 2–3 business days from the U.S.

LGMN-BIOTIN — affinity purified Rabbit antibody against Legumain. Validated for ELISA, IP, WB. Reacts with Human, Mouse, Rat.

Specifications

Catalog numberLGMN-BIOTIN
TargetLegumain
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationsELISA, IP, WB
ConjugateBIOTIN
PurityAffinity Purified
ImmunogenSynthetic peptide taken within amino acid region 100-150 on human Legumain protein.
Size100 µg
Storage-20°C
UniProtQ99538

About this target

Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of intern. In the zymogen form, the uncleaved propeptide blocks access to the active site. Subcellular location: Lysosome. Expression: Ubiquitous. Particularly abundant in kidney, heart and placenta.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.