MLKL Positive Control

Catalog no. PC-MLKL · Research Use Only

$200 per 5 applications. Ships within 2–3 business days from the U.S.

PC-MLKL — affinity-purified Rabbit antibody against MLKL. Validated for WB.

Specifications

Catalog numberPC-MLKL
TargetMLKL
ApplicationsWB
ConjugateUnconjugated
Size5 applications
Storage-20°C
UniProtQ9D2Y4

About this target

MLKL Positive Control is a Western blot positive control for MLKL antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Does not have protein kinase activity. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Subcellular location: Cytoplasm. Cell membrane. Nucleus. Note=Localizes to the cytoplasm and translocates to the plasma membrane on necroptosis induction. Localizes to the nucleus in response to orthomyxoviruses infection.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.