Parkin Blocking Peptide
Catalog no. P-PARK · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-PARK — affinity-purified Rabbit antibody against Parkin. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-PARK |
|---|---|
| Target | Parkin |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide taken within amino acid region 390-440 on human Parkin protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | O60260 |
About this target
Acts within a multiprotein E3 ubiquitin ligase complex, by catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. It also participates in the removal and/or detoxification of proteins that are abnormally folded or damaged. Forms E3 ubiquitin ligase complex with UBE2L3 or UBE2L6. Binds to C2A and C2B domains of SYTqq and interacts and regulates the turnovers of SEPT5. Subcellular location: Cytoplasm, Nucleus, Endoplasmic reticulum, Mitochondrion. Expression: Expressed highly in the brain, and is also expressed in the heart, testis and skeletal muscle. Expression is down-regulated or absent in tumor biopsies and in the brain of PARK2 patients.
Documents
Related products
- Parkin Antibody (PARK-101AP)
- Parkin Antibody BIOTIN (PARK-BIOTIN)
- Parkin Antibody FITC (PARK-FITC)
- Parkin Positive Control (PC-PARK)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.