Progesterone Blocking Peptide

Catalog no. P-PGR-121 · Research Use Only

$155 per 250 µg. Ships within 2–3 business days from the U.S.

P-PGR-121 — affinity-purified Rabbit antibody against PGR. Validated for Immunodepletion, Immunocompetition.

Specifications

Catalog numberP-PGR-121
TargetPGR
ApplicationsImmunodepletion, Immunocompetition
ConjugateUnconjugated
ImmunogenSynthetic peptide corresponding to amino acids within region 400-450 on human DNA-binding protein SATB2 protein.
Size250 µg
Storage-20°C
UniProtP06401

About this target

Progesterone Blocking Peptide is the antigenic blocking peptide for the PGR antibody PGR-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as a transcriptional activator or repressor.; FUNCTION: [Isoform A]: Ligand-dependent transdominant repressor of steroid hormone receptor transcriptional activity including repression of its isoform B, MR and ER. Subcellular location: Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases.; SUBCELLULAR LOCATION: [Isoform A]: Nucleus. Cytoplasm.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.