Phospho-Cofilin Antibody
Catalog no. PCFL-140AP · Research Use Only
$375 per 100 µg. Ships within 2–3 business days from the U.S.
PCFL-140AP — affinity purified Rabbit antibody against Phospho-Cofilin. Validated for ELISA, IP, WB. Reacts with Human, Mouse, Rat.
Specifications
| Catalog number | PCFL-140AP |
|---|---|
| Target | Phospho-Cofilin |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IP, WB |
| Conjugate | Unconjugated |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide corresponding to amino acids within region 1-50 on human Phosphorylated Cofilin. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | P23528 |
About this target
Phospho-Cofilin Antibody (PCFL-140AP) is an affinity-purified rabbit polyclonal antibody against Phospho-Cofilin. It is listed for ELISA, IP, WB and reacts with Human, Mouse, Rat. For research use only. Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics. Required for the centralization of the mitotic spindle and symmetric division of zygotes. Plays a role in the regulation of cell morphology and cytoskeletal organization in epithelial cells. Subcellular location: Nucleus matrix. Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium.
Documents
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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.