Phospho-FGFR1 Blocking Peptide

Catalog no. P-PFGFR1 · Research Use Only

$195 per 250 µg. Ships within 2–3 business days from the U.S.

P-PFGFR1 — affinity-purified Rabbit antibody against Phospho-FGFR1. Validated for Immunodepletion, Immunocompetition.

Specifications

Catalog numberP-PFGFR1
TargetPhospho-FGFR1
ApplicationsImmunodepletion, Immunocompetition
ConjugateUnconjugated
ImmunogenSynthetic peptide taken within amino acid region 640-690 on human basic fibroblast growth factor receptor protein 1.
Size250 µg
Storage-20°C
UniProtP11362

About this target

Phospho-FGFR1 Blocking Peptide is the antigenic blocking peptide for the Phospho-FGFR1 antibody PFGFR1-140AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Subcellular location: Cell membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm, cytosol. Cytoplasmic vesicle. Note=After ligand binding, both receptor and ligand are rapidly internalized.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.