Phospho-Slingshot homolog 1 Blocking Peptide

Catalog no. P-PSISHT · Research Use Only

$195 per 250 µg. Ships within 2–3 business days from the U.S.

P-PSISHT — affinity-purified Rabbit antibody against Phospho-Slingshot homolog 1. Validated for Immunodepletion, Immunocompetition.

Specifications

Catalog numberP-PSISHT
TargetPhospho-Slingshot homolog 1
ApplicationsImmunodepletion, Immunocompetition
ConjugateUnconjugated
ImmunogenPhosphorylated synthetic peptide corresponding to unique amino acid sequence on Slingshot homolog 1 protein.
Size250 µg
Storage-20°C
UniProtQ8WYL5

About this target

Phospho-Slingshot homolog 1 Blocking Peptide is the antigenic blocking peptide for the Phospho-Slingshot homolog 1 antibody PSISHT-140AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein. Subcellular location: Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cleavage furrow. Midbody. Note=Also recruited to actin rich membrane protrusions such as lamellipodia, which may allow local control of actin dynamics at sites of cell locomotion.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.