PREX2 Blocking Peptide

Catalog no. P-PREX2 · Research Use Only

$155 per 250 µg. Ships within 2–3 business days from the U.S.

P-PREX2 — affinity-purified Rabbit antibody against PREX2. Validated for Immunodepletion, Immunocompetition.

Specifications

Catalog numberP-PREX2
TargetPREX2
ApplicationsImmunodepletion, Immunocompetition
ConjugateUnconjugated
ImmunogenSynthetic peptide taken within amino acid region 720-900 on PREX2 protein.
Size250 µg
Storage-20°C
UniProtQ70Z35

About this target

PREX2 Blocking Peptide is the antigenic blocking peptide for the PREX2 antibody PREX2-201AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.