Progesterone Receptor Blocking Peptide

Catalog no. P-PGR.112 · Research Use Only

$155 per 250 µg. Ships within 2–3 business days from the U.S.

P-PGR.112 — affinity-purified Rabbit antibody against Progesterone Receptor. Validated for Immunodepletion, Immunocompetition.

Specifications

Catalog numberP-PGR.112
TargetProgesterone Receptor
ApplicationsImmunodepletion, Immunocompetition
ConjugateUnconjugated
ImmunogenSynthetic peptide taken within amino acid region 350-400 on human Progesterone receptor protein.
Size250 µg
Storage-20°C
UniProtP06401

About this target

Progesterone Receptor Blocking Peptide is the antigenic blocking peptide for the Progesterone Receptor antibody PGR-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as a transcriptional activator or repressor.; FUNCTION: [Isoform A]: Ligand-dependent transdominant repressor of steroid hormone receptor transcriptional activity including repression of its isoform B, MR and ER. Subcellular location: Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases.; SUBCELLULAR LOCATION: [Isoform A]: Nucleus. Cytoplasm.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.