PRP19 Blocking Peptide

Catalog no. P-PRP19F · Research Use Only

$155 per 250 µg. Ships within 2–3 business days from the U.S.

P-PRP19F — affinity-purified Rabbit antibody against PRP19. Validated for Immunodepletion, Immunocompetition.

Specifications

Catalog numberP-PRP19F
TargetPRP19
ApplicationsImmunodepletion, Immunocompetition
ConjugateUnconjugated
ImmunogenSynthetic peptide taken within amino acid region 200-300 on rat PRP19F protein.
Size250 µg
Storage-20°C
UniProtQ9JMJ4

About this target

PRP19 Blocking Peptide is the antigenic blocking peptide for the PRP19 antibody PRP19F-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome. Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates 'Lys-63'-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 component PRPF8 and stabilizes the U4/U5/U6 tri-snRNP spliceosomal complex. Subcellular location: Nucleus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Lipid droplet. Note=Nucleoplasmic in interphase cells. Irregularly distributed in anaphase cells.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.