RASGRF2 Blocking Peptide
Catalog no. P-RASGRF2 · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-RASGRF2 — affinity-purified Rabbit antibody against RASGRF2. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-RASGRF2 |
|---|---|
| Target | RASGRF2 |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide taken within amino acid region 1100-1200 on human RASGRF2 protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | O14827 |
About this target
Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Homooligomer and heterooligomer with RASGRF1. Interacts with Ras and RAC1. Interacts in a calcium-dependent manner with calmodulin (by similarity). Subcellular location: Cytoplasm, Cell membrane; Peripheral membrane protein, Endoplasmic reticulum membrane; Peripheral membrane protein. Expression: Widely expressed with higher expression in the brain, followed by heart, lung, pancreas and kidney. Detected in placenta. Expressed in brain and lung (at protein level).
Documents
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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.