SARS CoV-2 Spike Glycoprotein Blocking Peptide

Catalog no. P-SARSCOV2S-112 · Research Use Only

$155 per 250 µg. Ships within 2–3 business days from the U.S.

P-SARSCOV2S-112 — affinity-purified Rabbit antibody against SARS CoV-2 Spike Glycoprotein. Validated for Immunodepletion, Immunocompetition.

Specifications

Catalog numberP-SARSCOV2S-112
TargetSARS CoV-2 Spike Glycoprotein
ApplicationsImmunodepletion, Immunocompetition
ConjugateUnconjugated
ImmunogenSynthetic peptide corresponding to amino acids within region on 450-550 on SARS CoV-2 Spike Glycoprotein.
Size250 µg
Storage-20°C
UniProtP0DTC2

About this target

SARS CoV-2 Spike Glycoprotein Blocking Peptide is the antigenic blocking peptide for the SARS CoV-2 Spike Glycoprotein antibody SARSCOV2S-112AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. [Spike protein S1]: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. The major receptor is host ACE2. When S2/S2' has been cleaved, binding to the receptor triggers direct fusion at the cell membrane. When S2/S2' has not been cleaved, binding to the receptor results in internalization of the virus by endocytosis using host TFRC and GRM2 and leading to fusion of the virion membrane with the host endosomal membrane. Alternatively, may use NRP1/NRP2 and integrin as entry receptors. Subcellular location: Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.