Von Hippel Lindau Antibody

Catalog no. PVHL-101AP · Research Use Only

$285 per 100 µg. Ships within 2–3 business days from the U.S.

PVHL-101AP — affinity purified Rabbit antibody against Von Hippel Lindau. Validated for ELISA, IHC, IP, WB. Reacts with Human, Monkey, Mouse, Rat.

Specifications

Catalog numberPVHL-101AP
TargetVon Hippel Lindau
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ReactivityHuman, Monkey, Mouse, Rat
ApplicationsELISA, IHC, IP, WB
ConjugateUnconjugated
PurityAffinity Purified
ImmunogenSynthetic peptide taken within amino acid region 130-200 on human Von Hippel-Lindau disease tumor suppressor protein.
Size100 µg
Storage-20°C
UniProtP40337

About this target

Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF. Belongs to the VHL family. Subcellular location: Cytoplasm, Peripheral membrane protein, nucleus. Expression: Expressed in the adult and fetal brain and kidney.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.