Y Box Transcription Factor Blocking Peptide
Catalog no. P-PYBX1 · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-PYBX1 — affinity-purified Rabbit antibody against Phospho-YBX1. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-PYBX1 |
|---|---|
| Target | Phospho-YBX1 |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide taken within amino acid region 177-226 on Phosphorylated Y Box Transcription Factor protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | P62960 |
About this target
Y Box Transcription Factor Blocking Peptide is the antigenic blocking peptide for the Phospho-YBX1 antibody PYBX1-140AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. DNA- and RNA-binding protein involved in various processes, such as translational repression, RNA stabilization, mRNA splicing, DNA repair and transcription regulation. Predominantly acts as a RNA-binding protein: binds preferentially to the 5'-[CU]CUGCG-3' RNA motif and specifically recognizes mRNA transcripts modified by C5-methylcytosine (m5C). Promotes mRNA stabilization: acts by binding to m5C-containing mRNAs and recruiting the mRNA stability maintainer ELAVL1, thereby preventing mRNA decay. Component of the CRD-mediated complex that promotes MYC mRNA stability. Subcellular location: Cytoplasm. Nucleus. Cytoplasmic granule. Secreted. Secreted, extracellular exosome. Cytoplasm, P-body. Note=Predominantly cytoplasmic in proliferating cells. Cytotoxic stress and DNA damage enhance translocation to the nucleus.
Documents
Related products
- Y Box Transcription Factor Antibody Positve Control (PC-PYBX1)
- Phospho-specific Y Box Transcription Factor (Serine 207) Antibody (PYBX1-140AP)
- Y Box Transcription Factor Antibody BIOTIN (PYBX1-BIOTIN)
- Phospho-specific Y Box Transcription Factor (Serine 207) Antibody FITC (PYBX1-FITC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.