General Information |
|
Product |
ADCY5 Peptide |
Description |
Antigenic Blocking Peptide Adenylyl cyclase type 5 |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptide corresponding to unique amino acid sequence on rat Particulate Adenylyl Cyclase 5 protein. |
Accession # |
GenBank: M96159.1 |
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|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
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|
Competition/Depletion assay |
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Uniprot # |
|
Overview |
Membrane bound calcium-inhibitable adenylyl cyclase. |
Molecular Function |
Adenylate cyclase activity; cAMP biosynthesis; ATP-binding; Magnesium; Metal binding; Nucleotide-binding |
Subcellular Location |
Membrane; Multi-pass membrane protein; Cell projection; cilium |
Structure |
Part of a complex containing AKAP5, ADCY6, PDE4C and PKD2. Interacts with RAF1. |
Alternative Nomenclature |
AC 5 antibody Adcy5 antibody Adenylate cyclase type V antibody Adenylyl cyclase 5 antibody ATP pyrophosphate-lyase 5 antibody |
Protein information supplied by UniProt
Fabgennix ADCY5 Antibody has been used in 9 Publications |
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Akkerman, Sven et al. “PDE5 Inhibition Improves Object Memory in Standard Housed Rats but Not in Rats Housed in an Enriched Environment: Implications for Memory Models?” Ed. Patrizia Campolongo. PLoS ONE 9.11 (2014): e111692.
|
Western Blot; Rat |
Kwon, Ronald Y. et al. “Primary Cilium-Dependent Mechanosensing Is Mediated by Adenylyl Cyclase 6 and Cyclic AMP in Bone Cells.” The FASEB Journal 24.8 (2010): 2859–2868. PMC2909282
|
Confocal Microscopy, Immunofluorescence; Human |
Masyuk, Anatoliy I. et al. “Cholangiocyte Primary Cilia Are Chemosensory Organelles That Detect Biliary Nucleotides via P2Y12 Purinergic Receptors.”American Journal of Physiology - Gastrointestinal and Liver Physiology295.4 (2008): G725–G734. PMC2575915
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Confocal Microscopy, Immunofluorescence; Rat |
Ortiz-Capisano, M. Cecilia, et al. "Adenylyl cyclase isoform v mediates renin release from juxtaglomerular cells." Hypertension 49.3 (2007): 618-624.PMID17190869
|
Confocal Microscopy, Immunofluorescence, Western Blot; Rat |
Wang, Shyi-Chyi et al. “Regulation of Type V Adenylate Cyclase by Ric8a, a Guanine Nucleotide Exchange Factor.” The Biochemical Journal 406.Pt 3 (2007): 383–388. PMC2049038
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Immunocytochemistry; Rat |
Ivanov, Alexander et al. “Adenylate Cyclase 5 and KCa1.1 Channel Are Required for EGFR up-Regulation of PCNA in Native Contractile Rat Basilar Artery Smooth Muscle.” The Journal of Physiology 570.Pt 1 (2006): 73–84. PMC1464296
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Confocal Microscopy, Immunofluorescence, Western Blot; Rat |
Grünberger, Christian, et al. "The Calcium Paradoxon of Renin Release Calcium Suppresses Renin Exocytosis by Inhibition of Calcium-Dependent Adenylate Cyclases AC5 and AC6." Circulation research 99.11 (2006): 1197-1206.
|
Western Blot; Rat |
Masyuk, Anatoliy I. et al. “Cholangiocyte Cilia Detect Changes in Luminal Fluid Flow and Transmit Them into Intracellular Ca2+ and cAMP Signaling.”Gastroenterology 131.3 (2006): 911–920. PMC1866168
|
Confocal Microscopy, Immunofluorescence; Rat |
Kolachala, Vasantha, et al. "Interferon-γ down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase." Journal of Biological Chemistry 280.6 (2005): 4048-4057. PMID15550390
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Western Blot; Human |
Publishing research using PAC-501AP? Please let us know, we can cite the reference in this datasheet.
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