General Information |
|
Product |
Dopamine D2 Receptor Antibody BIOTIN |
Description |
BIOTIN-Conjugated Dopamine Receptor subtype D2 Antibody |
Verified Applications |
CM, ELISA, ICC, IF, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide corresponding to unique sequence on human Dopamine D2 Receptor protein. |
Accession # |
GenBank: AAA52328 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.55µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20°C for long term storage |
|
|
ELISA |
1:50,000 |
Immunocytochemistry |
1:200 |
Immunofluorescence |
1:200 |
Immunohistochemistry |
1:200 |
Immunoprecipitation |
1:200 |
Western Blot |
1:1,000-1:1,5000 |
|
|
Uniprot # |
|
Overview |
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. |
Molecular Function |
Dopamine Binding; Potassium Channel Regulator activity; Identical Protein binding |
Subcellular Location |
Cell membrane; Multi-pass membrane protein |
Structure |
Forms homo- and heterooligomers with DRD4. The interaction with DRD4 may modulate agonist-induced downstream signaling. Interacts with GPRASP1, PPP1R9B and CLIC6 (By similarity). Interacts with CADPS and CADPS2. Interacts with ARRB2 (By similarity). Interacts with KCNA2 (By similarity). Interacts with GNAI1 (PubMed:17264214). Interacts with GNAI2 isoform sGi2, the interaction allows the creation of an intracellular pool of DRD2 that can be released to cell surface upon agonist stimulation. Interacts with HTR2A. |
Alternative Nomenclature |
D(2) dopamine receptor antibody D2 dopamine receptor antibody D2DR antibody D2R antibody Dopamine D2 receptor antibody DRD2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-D2R.2 | |||
|
D2R-212AP | |||
|
D2R.2-FITC | |||
|
PC-D2R | |||
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