General Information
Product
Epac1 Antibody FITC-Conjugated
Description
FITC-Conjugated Rap Guanine Nucleotide Exchange Factor 3 Antibody N-epitope
Verified Applications
CM, ELISA, ICC, IF, IHC, WB
Host
Rabbit
Species Cross Reactivity
Horse, Human, Mouse, Rat
Immunogen
Synthetic peptide corresponding to amino acid region 9-26 of Epac1, peptide was covalently modified.
Synthetic peptide:
PRSCSYQLLLEHQRPSCI
Accession #
GenBank: AAD12740.1
Physical Properties
Quantity
100 µg
Volume
200 µl
Concentration
0.59 µg/µl in antibody stabilization buffer
Form
FITC-Conjugated
Clonality
Polyclonal
Determinant
N-epitope
Storage
-20⁰C for long term storage
Application Protocol
Confocal Microscopy
1:200
DB
1:10,000
ELISA
Immunocytochemistry
Immunofluorescence
Immunohistochemistry
Western Blot
1:500
Protein
Uniprot #
O95398
Overview
Guanine nucleotide exchange factor for RAP1A and RAP2A small GTPases that are activated by binding cAMP
Molecular Function
cAMP-binding; Nucleotide-binding
Subcellular Location
Endomembrane system
Expression
Widely expressed with highest levels in kidney, heart, thyroid and brain
Structure
Interacts with PDE3B
Alternative Nomenclature
bcm910 antibody
CGEF 1 antibody
Epac 1 antibody
EPAC antibody
Exchange protein directly activated by cAMP 1 antibody
MGC21410 antibody
RAP guanine nucleotide exchange factor antibody
RAPGEF3 antibody
Protein information supplied by UniProt
Fabgennix Epac1 Antibody has been used in 1 Publication
McPartlin, L.A., P.E. Visconti, and S.J. Bedford-Guaus. “Guanine-Nucleotide Exchange Factors (RAPGEF3/RAPGEF4) Induce Sperm Membrane Depolarization and Acrosomal Exocytosis in Capacitated Stallion Sperm.”Biology of Reproduction 85.1 (2011): 179–188. PMC3123385
Confocal Microscopy, Immunofluorescence, Western Blot; Horse, Mouse
Publishing research using EPAC-101AP? Please let us know, we can cite the reference in this datasheet.
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(c) FabGennix International Inc.