FOXO3A Positive Control

General Information

Product

FOXO3 Positive Control

Description

Western Blot Positive Control Forkhead box protein O3

Verified Applications

WB

Immunogen

Purified protein

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

O43524

Overview

Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.

Molecular Function

Activator

Subcellular Location

Cytoplasm, Nucleus

Expression

Ubiquitous

Structure

Contains 1 fork-head DNA-binding domain.

Alternative Nomenclature

AF6q21 antibody
FKHR2 antibody
FKHRL 1 antibody
FKHRL1 antibody
Forkhead box protein O3 antibody
Forkhead box protein O3A antibody
Forkhead Drosophila homolog of in rhabdomyosarcoma like 1 antibody
Forkhead in rhabdomyosarcoma like 1 antibody
FOX O3A antibody
FOXO2 antibody
foxo3 antibody
FOXO3A antibody