General Information |
|
Product |
FOXO3 Positive Control |
Description |
Western Blot Positive Control Forkhead box protein O3 |
Verified Applications |
WB |
Immunogen |
Purified protein |
|
|
Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
|
|
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation. |
Molecular Function |
Activator |
Subcellular Location |
Cytoplasm, Nucleus |
Expression |
Ubiquitous |
Structure |
Contains 1 fork-head DNA-binding domain. |
Alternative Nomenclature |
AF6q21 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
FOXO3A-101AP | |||
|
FOXO3A-BIOTIN | |||
|
FOXO3A-FITC | |||
|
P-FOXO3A | |||
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